How to succeed with PRF
The use of Blood Concentrates is becoming more and more popular in medical Aesthetics.
Patients like the idea of using their own cells instead of a synthetic alternative in their quest for a younger and fresher look.
EZ PRF is the result of years of experience and study. Consequently, we’ve found what we think is the ULTIMATE blood concentrate!
Not only does EZPRF contain more platelets per mcL, it also has leukocytes (WBC) & mesenchymal stem cell!
We could also call it the "Platelet, Leukocyte & Mesenchymal-stem-cells Concentrate”, but that would be a bit long, wouldn’t it? (#PLMC)
The fact that the plasma actually clots into fibrin allows for a much slower release of the Growth factor and cytokines.
We have more cells, resulting in more GFs, kept alive longer and released for a much longer period of time.
In order to obtain PRP, it is necessary to spin the tubes at up to 6x the G-Force of the EZPRF process.
The idea of the high spin method is to eliminate all Red Blood Cells (RBC), by pushing them down with gravitational force.
It's a good idea, but spinning it too fast, for too long, PRP methods also eliminate the cells that we DO want.
This is High School Biology: Our tubes are 100% Natural and devoid of any anti-coagulant. As a result, fibrinogen molecules can be converted by thrombin into fibrin during blood clot formation.
We're only using about 1/10th of the volume collected. And because we're spinning at a very low G-Force, the platelet recovery is very close to 100%!
Below, we're explaining why claims of 5x the concentration while using up to 1/2 of the collected volume is mathematically impossible!
There seems to be a debate in the scientific community about the White Blood Cells and their effect on the healing process. You'll get a different conclusion depending on who's financing the study.
We are creating what’s called a controlled inflammatory response and leukocytes are the cells associated with inflammatory response.
When PRP companies measure their platelet concentration, they usually use the bottom of their concentrate, the closest possible to the separating gel.
We've discussed earlier that spinning too fast sends the cells to the bottom. It also creates an imbalanced concentrate. The higher we collect, the less concentrated.
Let's have some fun with very simple math! :)
There are 20 Sheep in a 10 acre field.
That gives us a concentration of 2 sheep per acre.
Let's push all the sheep to the right 1/2 of the field. This is the equivalent of moving all the platelets on the top 1/2 of the tube.
We now have 4 sheep per acre, which equals to 2x the sheep concentration.
(This is similar to PRP: 1/2 the initial volume = max 2x the concentration)
If we move them all to 1/5 of the field, then we have 10 sheep per acre, which equals to 5x the concentration.
That is when we're able to retain 100% of the sheep (or a sheep recovery of 100%)
Otherwise, you're just creating Platelets (or sheep) out of thin air.
The proprietary EZPRF tubes and centrifuge settings are designed to create an injectable blood concentrate rich in platelets, leukocytes and Mesenchymal stem cells.
The EZ4K Kit contains everything needed for your ezPRF procedure, up to around 6cc of usable blood concentrate:
The EZMINISPIN is the smallest centrifuge on the market - capable of hosting up to 6 x 13mL test tubes. It has been pre-configured with our two customized EZPRF settings, and retains the ability to be set manually should the user feel the need to use a different centrifugation speed and time.
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